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Sample size calculation for clinical trials: the impact of clinician beliefs

The UK Medical Research Council (MRC) randomized trial of gastric surgery, ST01, compared conventional (D1) with radical (D2) surgery. Sample size estimation was based upon the consensus opinion of the surgical members of the design team, which suggested that a change in 5-year survival from 20% (D1...

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Main Authors: Fayers, P M, Cuschieri, A, Fielding, J, Craven, J, Uscinska, B, Freedman, L S
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363196/
https://ncbi.nlm.nih.gov/pubmed/10638992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.1999.0902
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