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The influenza virus variant A/FM/1/47-MA possesses single amino acid replacements in the hemagglutinin, controlling virulence, and in the matrix protein, controlling virulence as well as growth.

Genetic analysis of mouse-adapted influenza virus variant A/FM/1/47 (FM) MA has previously identified four genome segments, 4, 5, 7, and 8, that are statistically associated with virulence. On sequencing these genome segments, we found single amino acid replacements at amino acid 47 of the HA2 subun...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Smeenk, C A, Brown, E G
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1994
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236317/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8254767/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.1.530-534.1994
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