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Chromosomal aberrations in human hepatocellular carcinomas associated with hepatitis C virus infection detected by comparative genomic hybridization

Thirty-five hepatocellular carcinomas (HCCs) associated with hepatitis C virus (HCV) were analysed by comparative genomic hybridization (CGH), to screen for changes in copy-number of DNA sequences. Chromosomal losses were noted in 1p34–36 (37%), 4q12–21 (48%), 5q13–21 (35%), 6q13–16 (23%), 8p21–23 (...

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Detalhes bibliográficos
Main Authors: Sakakura, C, Hagiwara, A, Taniguchi, H, Yamaguchi, T, Yamagishi, H, Takahashi, T, Koyama, K, Nakamura, Y, Abe, T, Inazawa, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363156/
https://ncbi.nlm.nih.gov/pubmed/10471057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690638
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