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CDKN2A gene inactivation in epithelial sporadic ovarian cancer

The tumour suppressor gene CDKN2A, located on chromosome 9p21, encodes the cell cycle regulatory protein p16. Inactivation of the CDKN2A gene could lead to uncontrolled cell growth. In order to determine the role of CDKN2A in the development of sporadic ovarian cancer, loss of heterozygosity at 9p21...

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Autores principales: Niederacher, D, Yan, H-Y, An, H-X, Bender, H G, Beckmann, M W
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 1999
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363140/
https://ncbi.nlm.nih.gov/pubmed/10471040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690621
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