Growth dysregulation and p53 accumulation in human primary colorectal cancer

p53 accumulation is common in colorectal cancer, but effects on growth homeostasis are unclear. In this study, DNA content, cell cycle phase fractions and DNA strand-breaks consistent with apoptosis were assessed by flow cytometry in 42 fresh primary colorectal tumours and matched normal mucosa. p53...

Full description

Saved in:
Bibliographic Details
Main Authors: Watson, D S, Brotherick, I, Shenton, B K, Wilson, R G, Campbell, F C
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1999
Subjects:
Regular Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363047/
https://ncbi.nlm.nih.gov/pubmed/10362117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690464
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items