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Growth dysregulation and p53 accumulation in human primary colorectal cancer
p53 accumulation is common in colorectal cancer, but effects on growth homeostasis are unclear. In this study, DNA content, cell cycle phase fractions and DNA strand-breaks consistent with apoptosis were assessed by flow cytometry in 42 fresh primary colorectal tumours and matched normal mucosa. p53...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
1999
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2363047/ https://ncbi.nlm.nih.gov/pubmed/10362117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690464 |
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