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Induced extrusion of DNA from the capsid of herpes simplex virus type 1.

DNA-filled capsids (C capsids) of herpes simplex virus type 1 were treated in vitro with guanidine-HCl (GuHCl) and analyzed for DNA loss by sucrose density gradient ultracentrifugation and electron microscopy. DNA was found to be lost quantitatively from virtually all capsids treated with GuHCl at c...

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Detalhes bibliográficos
Main Authors: Newcomb, W W, Brown, J C
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC236303/
https://ncbi.nlm.nih.gov/pubmed/8254753
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