Loss of chromosome 10 is an independent prognostic factor in high-grade gliomas

Loss of heterozygosity (LOH) for chromosome 10 is the most frequent genetic abnormality observed in high-grade gliomas. We have used fluorescent microsatellite markers to examine a series of 83 patients, 34 with anaplastic astrocytoma (grade 3) and 49 with glioblastoma multiforme (grade 4), for LOH...

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Detalhes bibliográficos
Main Authors: Balesaria, S, Brock, C, Bower, M, Clark, J, Nicholson, S K, Lewis, P, de Sanctis, S, Evans, H, Peterson, D, Mendoza, N, Glaser, M G, Newlands, E S, Fisher, R A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1999
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362970/
https://ncbi.nlm.nih.gov/pubmed/10604735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6693403
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