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T-cell receptors from virus-specific cytotoxic T lymphocytes recognizing a single immunodominant nine-amino-acid viral epitope show marked diversity.

Following infection of the H-2d mouse by lymphocytic choriomeningitis virus, the newly generated cytotoxic T lymphocyte (CTL) response is focused to a single 9-amino-acid peptide sequence (epitope) of the virus. More than 96% of the primary, secondary, and clonal CTL respond to this lymphocytic chor...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Horwitz, M S, Yanagi, Y, Oldstone, M B
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236295/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7504738/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.1.352-357.1994
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