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Predictive value of decreased p27(Kip1) protein expression for the recurrence-free and long-term survival of prostate cancer patients

The p27(Kip1) gene has been identified as inductor of cell cycle arrest at the G1 checkpoint to prevent entry of somatic cells into the S phase of the cell cycle when substantial DNA damage has occurred. It has been suggested that decreased expression of the p27(Kip1) protein may contribute to the d...

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Detalhes bibliográficos
Main Authors: Kuczyk, M, Machtens, S, Hradil, K, Schubach, J, Christian, W, Knüchel, R, Hartmann, J, Bokemeyer, C, Jonas, U, Serth, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362945/
https://ncbi.nlm.nih.gov/pubmed/10576664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690806
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