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Up-regulation of macrophage wnt gene expression in adenoma-carcinoma progression of human colorectal cancer

Defects in the APC-β-catenin pathway are common in colon cancer. We investigated whether aberrant regulation of upstream ligands stimulating this pathway occur in colon cancer. Using RNAase protection analysis, six out of eight wnt genes were expressed in 14 matched cases of normal, adenomatous and...

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Detalhes bibliográficos
Main Authors: Smith, K, Bui, T D, Poulsom, R, Kaklamanis, L, Williams, G, Harris, A L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362915/
https://ncbi.nlm.nih.gov/pubmed/10507776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690721
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