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Up-regulation of macrophage wnt gene expression in adenoma-carcinoma progression of human colorectal cancer
Defects in the APC-β-catenin pathway are common in colon cancer. We investigated whether aberrant regulation of upstream ligands stimulating this pathway occur in colon cancer. Using RNAase protection analysis, six out of eight wnt genes were expressed in 14 matched cases of normal, adenomatous and...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
1999
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2362915/ https://ncbi.nlm.nih.gov/pubmed/10507776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690721 |
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