Overexpression of IL-1ra gene up-regulates interleukin-1β converting enzyme (ICE) gene expression: possible mechanism underlying IL-1β-resistance of cancer cells

We investigated the interaction of endogenous interleukin (IL)-1β, IL-1ra, and interleukin-1β converting enzyme (ICE) in four human urological cancer cell lines, KU-19-19, KU-1, KU-2 and KU-19-20. Northern blot analysis showed that IL-1β gene was expressed in all cell lines. On the other hand, in KU...

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Detalhes bibliográficos
Main Authors: Sumitomo, M, Tachibana, M, Murai, M, Hayakawa, M, Nakamura, H, Takayanagi, A, Shimizu, N
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1999
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362876/
https://ncbi.nlm.nih.gov/pubmed/10496353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690688
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