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T-antigen kinase inhibits simian virus 40 DNA replication by phosphorylation of intact T antigen on serines 120 and 123.

Simian virus 40 (SV40) DNA replication begins after two large T-antigen hexamers assemble on the viral minimal origin of replication and locally unwind the template DNA. The activity of T antigen in this reaction is regulated by its phosphorylation state. A form of casein kinase I purified from HeLa...

Deskribapen osoa

Gorde:
Argitaratua izan da:J Virol
Egile Nagusiak: Cegielska, A, Moarefi, I, Fanning, E, Virshup, D M
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 1994
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236286/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8254738/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.1.269-275.1994
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