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Proteolytic activity of novel human immunodeficiency virus type 1 proteinase proteins from a precursor with a blocking mutation at the N terminus of the PR domain.

The mature human immunodeficiency virus type 1 proteinase (PR; 11 kDa) can cleave all interdomain junctions in the Gag and Gag-Pol polyprotein precursors. To determine the activity of the enzyme in its precursor form, we blocked release of mature PR from a truncated Gag-Pol polyprotein by introducin...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Virol
Egile Nagusiak: Zybarth, G, Kräusslich, H G, Partin, K, Carter, C
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 1994
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236283/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8254734/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.1.240-250.1994
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