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Effects of bryostatin-1 on chronic myeloid leukaemia-derived haematopoietic progenitors

Bryostatin-1 belongs to the family of macrocyclic lactones isolated from the marine bryozoan Bugula neritina and is a potent activator of protein kinase C (PKC). Bryostatin has been demonstrated to possess both in vivo and in vitro anti-leukaemic potential. In samples derived from chronic myeloid le...

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Detalhes bibliográficos
Main Authors: Thijsen, S F T, Schuurhuis, G J, Oostveen, J W van, Theijsmeijer, A P, van der Hem, K G, Odding, J H, Dräger, A M, Ossenkoppele, G J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362710/
https://ncbi.nlm.nih.gov/pubmed/10188883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690225
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