Fractionated administration of irinotecan and cisplatin for treatment of lung cancer: a phase I study

A combination chemotherapy of irinotecan (CPT-11) and cisplatin (CDDP) has been reported to be active for lung cancer. In the previous trial, however, diarrhoea and leucopenia became the major obstacle for sufficient dose escalation of CPT-11 to improve the treatment outcome. We conducted a phase I...

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Detalhes bibliográficos
Main Authors: Ueoka, H, Tabata, M, Kiura, K, Shibayama, T, Gemba, K, Segawa, Y, Chikamori, K, Yonei, T, Hiraki, S, Harada, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1999
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362688/
https://ncbi.nlm.nih.gov/pubmed/10070901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690157
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