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Exclusion of a major role for the PTEN tumour-suppressor gene in breast carcinomas
PTEN is a novel tumour-suppressor gene located on chromosomal band 10q23.3. This region displays frequent loss of heterozygosity (LOH) in a variety of human neoplasms including breast carcinomas. The detection of PTEN mutations in Cowden disease and in breast carcinoma cell lines suggests that PTEN...
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| Главные авторы: | , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
1999
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2362671/ https://ncbi.nlm.nih.gov/pubmed/10070865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690121 |
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