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Apoptotic activity is increased in parallel with the metaplasia–dysplasia–carcinoma sequence of the bronchial epithelium

A high level of apoptotic activity and an independence of apoptosis from the expression of p53 and bcl-2 have been observed in non-small-cell lung carcinoma. We examined 44 samples of normal, metaplastic and premalignant (i.e. mild, moderate and severe dysplasias and carcinoma in situ) bronchial epi...

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Detalhes bibliográficos
Main Authors: Törmänen, U, Nuorva, K, Soini, Y, Pääkkö, P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362669/
https://ncbi.nlm.nih.gov/pubmed/10070903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690159
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