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Alternative complement pathway activation fragment Bb in early pregnancy as a predictor of preeclampsia

OBJECTIVE: Preeclampsia is a multisystem disease classically defined on the basis of hypertension and proteinuria. As shown in animal studies, complement activation is associated with inflammation in the placenta and adverse pregnancy outcomes. The association between complement activation in humans...

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Bibliographic Details
Main Authors: Lynch, Anne M., Murphy, James R., Byers, Tim, Gibbs, Ronald S., Neville, Margaret C., Giclas, Patricia C., Salmon, Jane E., Holers, V. Michael
Format: Artigo
Language:Inglês
Published: 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362503/
https://ncbi.nlm.nih.gov/pubmed/18221926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2007.10.793
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