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Medroxyprogesterone acetate inhibits interleukin 6 secretion from KPL-4 human breast cancer cells both in vitro and in vivo: a possible mechanism of the anticachectic effect

Interleukin 6 (IL-6) is a multifunctional cytokine. Recent reports suggest that circulating IL-6 secreted from tumour cells plays an important role in cancer-induced cachexia. Medroxyprogesterone acetate (MPA) has been used as an endocrine therapeutic agent for patients with breast cancer. It has be...

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Detalhes bibliográficos
Main Authors: Kurebayashi, J, Yamamoto, S, Otsuki, T, Sonoo, H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362426/
https://ncbi.nlm.nih.gov/pubmed/10027341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690099
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