Phase 2 Study of an HIV-1 Canarypox Vaccine (vCP1452) Alone and in Combination With rgp120: Negative Results Fail to Trigger a Phase 3 Correlates Trial

BACKGROUND: A goal of T-cell HIV vaccines is to define the correlation between a vaccine-induced immune response and protection from HIV infection. We conducted a phase 2 trial to determine if a canarypox vaccine candidate (vCP1452) administered with rgp120 subunit protein would “qualify” for a tria...

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Detalhes bibliográficos
Main Authors: Russell, Nina D., Graham, Barney S., Keefer, Michael C., McElrath, M. Juliana, Self, Steve G., Weinhold, Kent J., Montefiori, David C., Ferrari, Guido, Horton, Helen, Tomaras, Georgia D., Gurunathan, Sanjay, Baglyos, Lynn, Frey, Sharon E., Mulligan, Mark J., Harro, Clayton D., Buchbinder, Susan P., Baden, Lindsey R., Blattner, William A., Koblin, Beryl A., Corey, Lawrence
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362395/
https://ncbi.nlm.nih.gov/pubmed/17106277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.qai.0000248356.48501.ff
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