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Synthesis and Evaluation of [(123)I] Labeled Iodovinyl Amino Acids Syn-, Anti-1-Amino-3-[2-iodoethenyl]-cyclobutane-1-carboxylic Acid and 1-Amino-3-iodomethylene-cyclobutane-1-carboxylic Acid as Potential SPECT Brain Tumor Imaging Agents

Syn- and anti-1-amino-3-[2-iodoethenyl]-cyclobutane-1-carboxylic acid (syn-, anti-IVACBC 16, 17) and their analogue 1-amino-3-iodomethylene-cyclobutane-1-carboxylic acid (gem-IVACBC 18) were synthesized and radioiodoinated with [(123)I] in 34%–43% delay-corrected yield. All these amino acids entered...

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Detalhes bibliográficos
Main Authors: Yu, Weiping, Williams, Larry, Malveaux, Eugene, Camp, Vernon M., Olson, Jeffrey J., Goodman, Mark M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362394/
https://ncbi.nlm.nih.gov/pubmed/18258425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.01.035
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