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Activation of raphe efferents to the medial prefrontal cortex by CRF; correlation with anxiety-like behavior

BACKGROUND: Parallel lines of research suggest that dysfunction affecting both corticotropin-releasing factor (CRF) and serotonin (5-HT) systems is involved in the pathophysiology of psychiatric illnesses such as anxiety and depression. The effect of CRF on behavior, and on the accompanying change i...

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Detalhes bibliográficos
Main Authors: Meloni, Edward G., Reedy, Catherine L., Cohen, Bruce M., Carlezon, William A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362385/
https://ncbi.nlm.nih.gov/pubmed/18061145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2007.10.016
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