Serum anti-p53 antibodies in gastric adenocarcinoma patients are associated with poor prognosis, lymph node metastasis and poorly differentiated nuclear grade

Mutation of the p53 tumour suppressor gene often leads to the accumulation of mutant p53 protein in tumour cells. Many cancer patients develop antibodies that recognize the overexpressed p53 protein. The presence of these antibodies is, in some tumour types, associated with poor prognosis. Gastric c...

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Main Authors: Wu, C-W, Lin, Y-Y, Chen, G-D, Chi, C-W, Carbone, D P, Chen, J-Y
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 1999
Teme:
Regular Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362310/
https://ncbi.nlm.nih.gov/pubmed/10408857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690382
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