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Biosynthesis of HLA-C heavy chains in melanoma cells with multiple defects in the expression of HLA-A, -B, -C molecules

Recent investigations have shown that malignant transformation may down-regulate the expression of class I HLA molecules, β(2)-microglobulin (β(2)m) and members of the antigen-processing machinery. In the present study, we HLA-genotyped and identified at a biochemical level the three (HLA-A25, -B8,...

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Autors principals: Martayan, A, Fraioli, R, Giorda, E, Setini, A, Ciccarelli, G, Delfino, L, Ferrara, G B, Giacomini, P
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362293/
https://ncbi.nlm.nih.gov/pubmed/10360639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690405
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