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A randomized phase II trial of 5-fluorouracil, with or without human interferon-β, for advanced colorectal cancer

This study compared the efficacy and safety of 5-fluorouracil (5-FU) monotherapy to that of 5-FU combined with natural human interferon-β (IFN-β) in patients with unresectable, advanced colorectal carcinoma. Forty-nine chemotherapy-naive patients were randomized to 5-FU alone or to the combination....

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Detalhes bibliográficos
Main Authors: Villar-Grimalt, A, Candel, M T, Massuti, B, Lizón, J, Sánchez, B, Frau, A, Gorostidi, B, Goedkoop, R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362283/
https://ncbi.nlm.nih.gov/pubmed/10360656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690422
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