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Human thyroid cancer cells as a source of iso-genic, iso-phenotypic cell lines with or without functional p53
Differentiated thyroid carcinomas (in contrast to the rarer anaplastic form) are unusual among human cancers in displaying a remarkably low frequency of p53 mutation and appear to retain wild-type (wt) p53 function as assessed by the response of derived cell lines to DNA damage. Using one such cell...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2362227/ https://ncbi.nlm.nih.gov/pubmed/10098744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690177 |
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