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Creatine and cyclocreatine treatment of human colon adenocarcinoma xenografts: (31)P and (1)H magnetic resonance spectroscopic studies
Creatine (Cr) and cyclocreatine (cyCr) have been shown to inhibit the growth of a variety of human and murine tumours. The purpose of this study was to evaluate the anti-tumour effect of these molecules in relation to drug accumulation, energy metabolism, tumour water accumulation and toxicity. Nude...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2362210/ https://ncbi.nlm.nih.gov/pubmed/9888469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690045 |
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