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Creatine and cyclocreatine treatment of human colon adenocarcinoma xenografts: (31)P and (1)H magnetic resonance spectroscopic studies

Creatine (Cr) and cyclocreatine (cyCr) have been shown to inhibit the growth of a variety of human and murine tumours. The purpose of this study was to evaluate the anti-tumour effect of these molecules in relation to drug accumulation, energy metabolism, tumour water accumulation and toxicity. Nude...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Kristensen, C A, Askenasy, N, Jain, R K, Koretsky, A P
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362210/
https://ncbi.nlm.nih.gov/pubmed/9888469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690045
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