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Tamoxifen induces oxidative stress and apoptosis in oestrogen receptor-negative human cancer cell lines

Recent data have demonstrated that the anti-oestrogen tamoxifen (TAM) is able to facilitate apoptosis in cancer cells not expressing oestrogen receptor (ER). In an attempt to identify the biochemical pathway for this phenomenon, we investigated the role of TAM as an oxidative stress agent. In two ER...

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Detalhes bibliográficos
Main Authors: Ferlini, C, Scambia, G, Marone, M, Distefano, M, Gaggini, C, Ferrandina, G, Fattorossi, A, Isola, G, Panici, P Benedetti, Mancuso, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362195/
https://ncbi.nlm.nih.gov/pubmed/9888466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690042
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