Tamoxifen induces oxidative stress and apoptosis in oestrogen receptor-negative human cancer cell lines

Recent data have demonstrated that the anti-oestrogen tamoxifen (TAM) is able to facilitate apoptosis in cancer cells not expressing oestrogen receptor (ER). In an attempt to identify the biochemical pathway for this phenomenon, we investigated the role of TAM as an oxidative stress agent. In two ER...

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Bibliografiska uppgifter
Huvudupphovsmän: Ferlini, C, Scambia, G, Marone, M, Distefano, M, Gaggini, C, Ferrandina, G, Fattorossi, A, Isola, G, Panici, P Benedetti, Mancuso, S
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 1999
Ämnen:
Regular Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362195/
https://ncbi.nlm.nih.gov/pubmed/9888466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690042
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