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Cooperative stimulation of vascular endothelial growth factor expression by hypoxia and reactive oxygen species: the effect of targeting vascular endothelial growth factor and oxidative stress in an orthotopic xenograft model of bladder carcinoma

Elevated thymidine phosphorylase has been shown to correlate with increased angiogenesis and poor prognosis in many cancers including transitional cell carcinoma of the bladder. In vitro studies have demonstrated that thymidine phosphorylase activity causes cellular oxidative stress and increases se...

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Detalhes bibliográficos
Main Authors: Brown, N S, Streeter, E H, Jones, A, Harris, A L, Bicknell, R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362032/
https://ncbi.nlm.nih.gov/pubmed/15841086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602522
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