Metallothionein crypt-restricted immunopositivity indices (MTCRII) correlate with aberrant crypt foci (ACF) in mouse colon

Metallothionein (MT) crypt-restricted immunopositivity indices (MTCRII) are colonic crypt stem cell mutation markers that may be induced early and in abundance after mutagen treatment. Metallothionein is the endogenous reporter gene for MTCRII, but is not typically implicated in the classical pathwa...

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Main Authors: Donnelly, E T, Bardwell, H, Thomas, G A, Williams, E D, Hoper, M, Crowe, P, McCluggage, W G, Stevenson, M, Phillips, D H, Hewer, A, Osborne, M R, Campbell, F C
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2005
Teme:
Translational Therapeutics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361830/
https://ncbi.nlm.nih.gov/pubmed/15928667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602633
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