Report of two protocol planned interim analyses in a randomised multicentre phase III study comparing capecitabine with fluorouracil and oxaliplatin with cisplatin in patients with advanced oesophagogastric cancer receiving ECF

The purpose of the study was to establish the optimal dose of capecitabine (X) to be used within a multicentre, randomised study evaluating the potential roles of oxaliplatin (O) and X in chemonaive patients (pts) with advanced oesophagogastric cancer. Two by two design was used, and pts were random...

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Главные авторы: Sumpter, K, Harper-Wynne, C, Cunningham, D, Rao, S, Tebbutt, N, Norman, A R, Ward, C, Iveson, T, Nicolson, M, Hickish, T, Hill, M, Oates, J
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2005
Предметы:
Clinical Study
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361798/
https://ncbi.nlm.nih.gov/pubmed/15928658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602572
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