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Targeting of Pseudorabies Virus Structural Proteins to Axons Requires Association of the Viral Us9 Protein with Lipid Rafts

The pseudorabies virus (PRV) Us9 protein plays a central role in targeting viral capsids and glycoproteins to axons of dissociated sympathetic neurons. As a result, Us9 null mutants are defective in anterograde transmission of infection in vivo. However, it is unclear how Us9 promotes axonal sorting...

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Detalhes bibliográficos
Main Authors: Lyman, Mathew G., Curanovic, Dusica, Enquist, Lynn W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361720/
https://ncbi.nlm.nih.gov/pubmed/18483549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000065
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