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Potential use of COX-2–aromatase inhibitor combinations in breast cancer
Cyclooxygenase-2 (COX-2) is overexpressed in several epithelial tumours, including breast cancer. Cyclooxygenase-2-positive tumours tend to be larger, higher grade, node-positive and HER-2/neu-positive. High COX-2 expression is associated with poor prognosis. Cyclooxygenase-2 inhibition reduces the...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
2005
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2361689/ https://ncbi.nlm.nih.gov/pubmed/16100520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602690 |
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