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Potential use of COX-2–aromatase inhibitor combinations in breast cancer

Cyclooxygenase-2 (COX-2) is overexpressed in several epithelial tumours, including breast cancer. Cyclooxygenase-2-positive tumours tend to be larger, higher grade, node-positive and HER-2/neu-positive. High COX-2 expression is associated with poor prognosis. Cyclooxygenase-2 inhibition reduces the...

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Autors principals: Bundred, N J, Barnes, N L P
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361689/
https://ncbi.nlm.nih.gov/pubmed/16100520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602690
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