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Effects of oestradiol and tamoxifen on VEGF, soluble VEGFR-1, and VEGFR-2 in breast cancer and endothelial cells
Angiogenesis is regulated by the balance between pro- and antiangiogenic factors. Vascular endothelial growth factor (VEGF), acting via the receptors VEGFR-1 and VEGFR-2, is a key mediator of tumour angiogenesis. The soluble form of the VEGF receptor-1 (sVEGFR-1) is an important negative regulator o...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2005
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2361685/ https://ncbi.nlm.nih.gov/pubmed/16234819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602824 |
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