Capecitabine and mitomycin C as third-line therapy for patients with metastatic colorectal cancer resistant to fluorouracil and irinotecan

Protracted venous infusion 5-fluorouracil (5FU) combined with mitomycin C (MMC) has demonstrated significant activity against metastatic colorectal cancer. Owing to potential synergy based upon upregulation of thymidine phosphorylase by MMC, the combination of capecitabine and MMC may improve outcom...

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Detalhes bibliográficos
Main Authors: Chong, G, Dickson, J L B, Cunningham, D, Norman, A R, Rao, S, Hill, M E, Price, T J, Oates, J, Tebbutt, N
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2005
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361607/
https://ncbi.nlm.nih.gov/pubmed/16091760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602733
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