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The endothelin B (ET(B)) receptor agonist IRL 1620 is highly vasoconstrictive in two syngeneic rat tumour lines: potential for selective tumour blood flow modification

The vascular effects of the endothelin B (ET(B)) receptor agonist IRL 1620 were investigated in the rat P22 carcinosarcoma and a range of normal tissues in BDIX rats. Tissue blood flow rate was calculated from measurements of tissue uptake of radiolabelled iodoantipyrine. A comparison of vascular ef...

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Detalhes bibliográficos
Main Authors: Cemazar, M, Wilson, I, Prise, V E, Bell, K M, Hill, S A, Tozer, G M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361472/
https://ncbi.nlm.nih.gov/pubmed/15970923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602672
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