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Cellular Basis for Arrhythmogenesis in an Experimental Model of the SQT1 Form of the Short QT Syndrome

BACKGROUND: Short QT syndrome (SQT) is a primary electrical disease associated with a high risk of sudden cardiac death. A gain-of-function in I(Kr), due to a mutation in KCNH2, underlies SQT1. OBJECTIVE: To examine the cellular basis for arrhythmogenesis in an experimental model of SQT1 created usi...

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Autori principali: Patel, Chinmay, Antzelevitch, Charles
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361425/
https://ncbi.nlm.nih.gov/pubmed/18362027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2008.01.022
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