A phase I and II study of 2-weekly irinotecan with capecitabine in advanced gastroesophageal adenocarcinoma

We investigated 2-weekly intravenous irinotecan combined with oral capecitabine in patients with advanced gastroesophageal adenocarcinoma. In phase I, doses were escalated in chemotherapy naïve or pretreated patients to establish maximum tolerated doses (MTD). In phase II, patients were treated at M...

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Detalhes bibliográficos
Main Authors: Burge, M E, Smith, D, Topham, C, Jackson, D P, Anthoney, D A, Halstead, F, Seymour, M T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2006
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361406/
https://ncbi.nlm.nih.gov/pubmed/16622464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603084
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