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Cyclin D1 A870G polymorphism and the risk of colorectal cancer and adenoma

Cyclin D1 (CCND1) plays a key role in cell cycle control, particularly in the transition from G(1) to S phase, which is regulated by cyclin-dependent kinases. A common adenine to guanine polymorphism (A870G) in the CCND1 gene has been associated with a longer-life protein and an increased risk of co...

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Main Authors: Schernhammer, E S, Tranah, G J, Giovannucci, E, Chan, A T, Ma, J, Colditz, G A, Hunter, D J, Willett, W C, Fuchs, C S
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361367/
https://ncbi.nlm.nih.gov/pubmed/16495921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603007
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