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Real-time PCR analysis of a 3895 bp mitochondrial DNA deletion in nonmelanoma skin cancer and its use as a quantitative marker for sunlight exposure in human skin

Previous findings from our own laboratory have shown that the frequency of occurrence (i.e. the simple presence or absence) of the 3895 bp mitochondrial DNA deletion is increased with increasing sun exposure. The present study has significantly extended this work by developing, validating and then u...

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Detalhes bibliográficos
Main Authors: Harbottle, A, Birch-Machin, M A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361359/
https://ncbi.nlm.nih.gov/pubmed/16721366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603178
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