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Expression of the proteolysis-inducing factor core peptide mRNA is upregulated in both tumour and adjacent normal tissue in gastro-oesophageal malignancy

Gastro-oesophageal cancer is associated with a high incidence of cachexia. Proteolysis-inducing factor (PIF) has been identified as a possible cachectic factor and studies suggest that PIF is produced exclusively by tumour cells. We investigated PIF core peptide (PIF-CP) mRNA expression in tumour an...

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Detalhes bibliográficos
Main Authors: Deans, D A C, Wigmore, S J, Gilmour, H, Tisdale, M J, Fearon, K C H, Ross, J A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361198/
https://ncbi.nlm.nih.gov/pubmed/16495932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602989
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