Survivin expression in in situ and invasive breast cancer relates to COX-2 expression and DCIS recurrence

In lung cancer cyclooxygenase-2 (COX-2) expression has been reported to stabilise survivin, an inhibitor of apoptosis (IAP) which prevents cell death by blocking activated caspases. COX-2 expression limits the ubiquitination of survivin, protecting it from degradation. To determine if COX-2 expressi...

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Bibliografiske detaljer
Main Authors: Barnes, N, Haywood, P, Flint, P, Knox, W F, Bundred, N J
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2006
Fag:
Molecular Diagnostics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361101/
https://ncbi.nlm.nih.gov/pubmed/16421596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602932
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