HapMap-based study of the 17q21 ERBB2 amplicon in susceptibility to breast cancer

ERBB2 is frequently amplified in breast tumours as part of a wide region of amplification on chromosome 17q21. This amplicon contains many candidate genes for breast cancer susceptibility. We used a genetic association study design to determine if common genetic variation (frequency ⩾5%) in a 400-kb...

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Detalhes bibliográficos
Main Authors: Benusiglio, P R, Pharoah, P D, Smith, P L, Lesueur, F, Conroy, D, Luben, R N, Dew, G, Jordan, C, Dunning, A, Easton, D F, Ponder, B A J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2006
Assuntos:
Genetics and Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360759/
https://ncbi.nlm.nih.gov/pubmed/17117180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603473
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