Molecular basis for sensitivity and acquired resistance to gefitinib in HER2-overexpressing human gastric cancer cell lines derived from liver metastasis

Gastric cancer metastasised to the liver was found to overexpress HER2 at a significantly higher incidence than primary gastric cancers. The purpose of the present study was to investigate the possibility of molecular therapy targeting HER2 overexpression in gastric cancer liver metastasis. We devel...

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Detalhes bibliográficos
Main Authors: Yokoyama, H, Ikehara, Y, Kodera, Y, Ikehara, S, Yatabe, Y, Mochizuki, Y, Koike, M, Fujiwara, M, Nakao, A, Tatematsu, M, Nakanishi, H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2006
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360749/
https://ncbi.nlm.nih.gov/pubmed/17088902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603459
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