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Cellular senescence in naevi and immortalisation in melanoma: a role for p16?
Cellular senescence, the irreversible proliferative arrest seen in somatic cells after a limited number of divisions, is considered a crucial barrier to cancer, but direct evidence for this in vivo was lacking until recently. The best-known form of human cell senescence is attributed to telomere sho...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2360676/ https://ncbi.nlm.nih.gov/pubmed/16880792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603283 |
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