Genetic and epigenetic alterations on the short arm of chromosome 11 are involved in a majority of sporadic Wilms' tumours

Wilms' tumour is one of the most common solid tumours of childhood. 11p13 (WT1 locus) and 11p15.5 (WT2 locus) are known to have genetic or epigenetic aberrations in these tumours. In Wilms' tumours, mutation of the Wilms tumour 1 (WT1) gene at the WT1 locus has been reported, and the WT2 l...

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Dettagli Bibliografici
Autori principali: Satoh, Y, Nakadate, H, Nakagawachi, T, Higashimoto, K, Joh, K, Masaki, Z, Uozumi, J, Kaneko, Y, Mukai, T, Soejima, H
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2006
Soggetti:
Genetics and Genomics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360663/
https://ncbi.nlm.nih.gov/pubmed/16909133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603302
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