Generation of tumour-specific cytotoxic T-cell clones from histocompatibility leucocyte antigen-identical siblings of patients with melanoma

Lymphodepletion and infusion of autologous expanded tumour-infiltrating lymphocytes is effective therapy for patients with malignant melanoma. Antitumour responses are likely to be mediated by HLA class I- and II-restricted immune responses directed at tumour antigens. We assessed whether the periph...

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Bibliographic Details
Main Authors: Gottlieb, D J, Li, Y-C, Lionello, I, Tanzarella, S, Marangolo, M, Bradstock, K F, Russo, V, Traversari, C
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2006
Subjects:
Translational Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360612/
https://ncbi.nlm.nih.gov/pubmed/16819544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603243
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