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EGFR mutation status in tumour-derived DNA from pleural effusion fluid is a practical basis for predicting the response to gefitinib

Epidermal growth factor receptor (EGFR) mutations are strong determinants of tumour response to EGFR tyrosine kinase inhibitors in non-small-cell lung cancer (NSCLC). Pleural effusion is a common complication of lung cancer. In this study, we assessed the feasibility of detection of EGFR mutations i...

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Main Authors: Kimura, H, Fujiwara, Y, Sone, T, Kunitoh, H, Tamura, T, Kasahara, K, Nishio, K
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360588/
https://ncbi.nlm.nih.gov/pubmed/17060940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603428
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