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FISH analysis of 107 prostate cancers shows that PTEN genomic deletion is associated with poor clinical outcome

This study examines the clinical impact of PTEN genomic deletions using fluorescence in situ hybridisation (FISH) analysis of 107 prostate cancers, with follow-up information covering a period of up to 10 years. Tissue microarray analysis using interphase FISH indicated that hemizygous PTEN losses w...

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Detalhes bibliográficos
Main Authors: Yoshimoto, M, Cunha, I W, Coudry, R A, Fonseca, F P, Torres, C H, Soares, F A, Squire, J A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360375/
https://ncbi.nlm.nih.gov/pubmed/17700571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603924
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